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KMID : 0363320160370030560
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Journal of Korean Oriental Internal Medicine
2016 Volume.37 No. 3 p.560 ~ p.567
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Effects of Herbal Medicine Injinchunggan-tang on Steroid-induced Symptoms in a Patient with Autoimmune Hepatitis-Primary Biliary Cirrhosis Overlap Syndrome: A Case Report
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Kim Ha-Yeon
Bae Jung-Han
Choi Eun-Sol
Jang Eun-Gyeong
Lee Jang-Hoon
Kim Young-Chul
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Abstract
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Objectives: The medical records, including laboratory test results, of a patient with autoimmune hepatitis (AIH)-primary biliary cirrhosis (PBC) overlap syndrome were reviewed to observe changes in steroid-induced adverse reactions before and after herbal medicine treatment.
Methods: We investigated the records of a 44-year-old female patient with AIH-PBC overlap syndrome treated at the Kyung Hee University Korean Medicine Hospital. Injinchunggan-tang and its modified decoctions were administered, and any changes inclinical manifestations as well as laboratory test results were monitored.
Results and Conclusions: Significant decreases in ALP, GGT, ALT, and AST levels were observed after oral administration of the herbal medicines. Improvements in steroid-induced symptoms (hyperglycemia, fatigue, and moon face) were also observed. Injinchunggan-tang and its modified prescriptions are promising candidates for proper management of AIH-PBC overlap syndrome.
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KEYWORD
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autoimmune hepatitis, primary biliary cirrhosis, steroids, Injinchunggan-tang
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